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We derived haESC3KO with quadruple frameshift mutations at Sfmbt2,Jade1,Smoc1,andGab1usingCRISPR-Cas9-mediated gene editing (D4-haESC3KO)(Figures S1D–S1H). After MII oocyte injectionofD4-haESC3KO,thereconstructedembryos(D4-embry-o3KO) were transferred into the oviduct of pseudopregnant mice (Figure 1E). However, development of D4-embryo3KO wasHezkuntzaren kalitatea hobetzeko 8/2013 Lege Organikoak, abenduaren 9koak, aldatu egin du maiatzaren 3ko 2/2006 Lege Organikoa. Hain zuzen, curriculumaren kontzeptua eta Estatuaren eta autonomia-erkidegoen arteko eskumenen banaketa aldatu ditu, Oinarrizko Hezkuntzako curriculuma Euskal Autonomia Erkidegoan ezartzen duen …Fig. 1 SCT 3KO primary CTLs are K b specific and non-MHC cross-reactive. (A) OVAp/K b SCT 3KO splenocytes stimulated with B6 splenocytes were cultured with RMA (H2 b) target cells in the absence or presence of monoclonal antibody. Data represent one experiment of six.

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Dec 13, 2022 · h3.3ko seeds germinated within two months after sowing were considered as germinated, and the rest seeds were discarded. The germination date of the first 12 germinated seeds was scored.

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First, we engineered 3KO·9TG pigs carrying 3KO to eliminate major xenoantigens and nine human transgenes (9TG) to enhance the immunological and coagulation compatibility between pigs and humans.

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