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Your liver has an enzyme called p450 that causes clobenzorex to go through debenzylation cleaving off the added benzyl molecule. It doesnt do this at very good rates so you are getting a lot of the parent drug (n 2 chlorobenzyl amphetamine). A lot of articles say the parent drug is also psychoactive and has a high 5ht affinity then reg d amp.
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Synonyms Clobenzorex HCl UNII BC6X5MB664 CAS Number 5843-53-8 Weight Average: 296.24 Monoisotopic: 295.089455 Chemical Formula C 16 H 19 Cl 2 N InChI Key ASTCUURTJCZRSC-ZOWNYOTGSA-N InChI
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Does the % of clobenzorex metabolized into amphetamine vary randomly? There is high individual variance in pharmacokinetics, and even more so with a prodrug. As far as I'm aware, there is little information about the metabolic pathway of clobenzorex. You might have some luck looking into benzphetamine as it also undergoes N-debenzylation.
Irritant. Other CAS. 1048649-80-4. 5843-53-8. Wikipedia. Clobenzorex hydrochloride. Dates. Modify: 2023-08-15. Clobenzorex hydrochloride, a chemical compound, is widely used in scientific research.Its versatile applications range from studying neurochemical processes to investigating potential therapeutic interventions.Amines. Antiobesity Preparations, Excl. Diet Products. Central Nervous System Stimulants. Centrally Acting Antiobesity Products. Ethylamines. Phenethylamines. Chemical Taxonomy Provided by Classyfire. Description. This compound belongs to the class of organic compounds known as amphetamines and derivatives.BedsAny1+2+3+4+5+ Use exact match Bathrooms Any1+1.5+2+3+4+ Home Type Select All Houses Townhomes Multi-family Condos/Co-ops Lots/Land Apartments …ITRAVIL IFA,CLOBENZOREX. FARMACOCINÉTICA Y FARMACODINAMIA: Farmacocinética: El Clobenzorex es bien absorbido en el tracto gastrointestinal, alcanzando su concentración máxima en 60 a 120 minutos y los niveles plasmáticos varían de 8 a 47 ng/ml. Clobenzorex se une a proteínas plasmáticas en aproximadamente 15% - 30%, se distribuye ampliamente en los tejidos.Buy Wholesale Obeclox Clobenzorex From Mexican Pharmacy Store. At Mexican Pharmacy Store, our products are of the highest quality. Our Obeclox Clobenzorex For Sale comes in 30 mg (30 Tablets). We’re passionate about our products, and we always strive to provide our customers with the best in both selection and quality. All of the …Clobenzorex, chemically (+)-V-[(2-chlorphenylmethyl]-amethylbenzeneethanamine, is a centrally acting anorectic. The drug is rapidly absorbed and excreted in the urine, mainly in the glucuronide form. It is partially metabolized to amphetamine. No data are available concerning its dependence potential in either animals or man and only a few ...The fecal elimination of clobenzorex consists of unchanged products, conjugated derivatives, urinary parahydroxyclobenzorex (1.5–6% of the administered dose) and amphetamine (15%). Among the adverse effects of clobenzorex are the consequences of vasoconstriction, including arterial hypertension and pulmonary artery hypertension.
Clobenzorex is a prodrug of D-Amphetamine. The 2-chlorobenzyl group is primarily cleaved through N-dealkylation via CYP3A4 into D-Amph. It's molecular weight is about double that of Amph, so the theoretical mass of Amph metabolites …
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